Custom Peptide Synthesis – A Brief Introduction

Technology has taken its counterpart in our lives. The introduction of custom peptide synthesis is one of the major contributions of commercial industry to the society. It is one of the most talked about topic of biochemistry, biology, biotechnology, pharmacology and molecular science. The advancement and development of various products related to the field of life sciences have given a good room for the growth of custom peptide synthesis in the industry.

To make it more clear, we can define it as the commercial production of peptides. These custom peptides could be defined as valuable tools in the field of biochemical laboratories. These researches help in creating and obtaining the valuable tools. These tools are further used in biochemical laboratories. To start with, synthetic oligo-peptides are one of the most commonly used custom peptide synthesis that are used in laboratories.

These are used extensively in research for structure function analysis. They are found to be helpful in offering the extended help for the development of binding assays, in the study of receptor or antagonist nature. It is essential to have in depth knowledge about it as it helps in determining the production of specific antibodies.

The peptides are synthesized for customized use by allowing them to make reactions with carboxyl group or C – Terminus of one amino acids to the part of N- Terminus of next amino acid in the chain. Hence, the chains of correlation between the two amino acids are used to bring out the desired results. These results could be further accelerated for the use of specific needs.

The optimized use of custom peptide synthesis could be done on both large as well as small scale. Large scale custom peptide synthesis requires the liquid medium of the solution or the solid state of the medium. However, the budget factor of peptides could be met with the use of peptides that are made up of less than 8 amino acids. These shorter chains of amino acids are economical and are used generally to meet the requirements. They are used in solution chemistry.

On the other hand, peptides that are larger than 8 residues are generally assembled by the use of solid phase chemistry. It is commonly known as solid phase peptide synthesis. They could be carried out either manually or assembled in a fully automatic fashion. The manual synthesis turned out to be more useful and beneficial as it allows a greater scale of flexibility and allows trouble shooting proactive decisions.

Depending upon the requirement, the peptide synthesis could be customized and can fulfill the requirements with a great perfection.